Dr. Samatha Bhat

Assistant Professor

Manipal Center for Biotherapeutics Research

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    • Assistant Professor in the Department of Biotherapeutics Research, MAHE, Manipal.
    • Academic coordinator and MSc course coordinator
    • Involved in teaching and research activities at DBR, MAHE, Manipal.
    • SLCM coordinator and cultural coordinator at DBR
    • Clean room facility in charge at DBR

SUBJECTS CURRENTLY TEACHING

Subject Semester / Year
Biotherapeutics Discovery and Development Semester I
Bioprocess Engineering Semester I
Biotherapeutic Discovery and Development Lab Semester I
Mini Research Project Semester II

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
Ph.D. Cancer Epigenetics Manipal Academy of Higher Education, Manipal 2015

Experience

Institution / Organisation Designation Role Tenure
Department of Biotherapeutics Research, MAHE Assistant Professor Teaching 2024 -till date
Stempeutics Research Pvt Ltd Deputy Manager and in charge- Production 2023-2024
Stempeutics Research Pvt Ltd Senior Research Scientist and In charge- Production 2020-2023
Stempeutics Research Pvt Ltd Research Scientist- Production 2015-2020
School of Life Sciences, MAHE CSIR Senior Research Fellow 2014-2015

  • Investigating the role of miRNAs in regulating stemness properties in cancer
  • Understanding epigenetic deregulation in cancer
  • Developing methylation-based biomarkers for screening and early diagnosis of cancer
  • Understanding and elucidating the signalling pathways, crosstalk’s between key regulatory molecules and their molecular mechanisms in cancer
  • Large scale manufacturing of adult stem cells for clinical applications, process development studies, understanding the mechanism of action of  mesenchymal stem cells and its applications in treatment of various disease indications
  • Cell free therapy-  Formulation development studies using secretomes derived from stem cells for biotherapeutic product development for regenerative applications

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Genetics, Molecular biology, Stem cells and Regenerative Medicine, Cell biology, Genetic engineering, Genomics and Proteomics

Area of Expertise

Epigenetics, Cell Signalling, Cell and Molecular Biology, Stem cells and Regenerative Medicine

Professional Affiliations & Contributions

Reviewer for BMC Cancer, Journals from Benthemscience.org

 

Awards and Honors:

  1. Dr. Vidya Ravi Memorial award for top Women Scientist in Stem Cell Therapy presented by Maruti Hospital, Department of Stem Cell Therapy and Regenerative Medicine, Trichy, Tamil Nadu, in the year 2024
  2. Dr. T M A Pai Gold Medal award for outstanding research publication for the year 2023 in appreciation for excellence in research presented by Manipal School of Life Sciences, MAHE, Manipal
  3. Dr. T M A Pai Gold Medal award for outstanding research publication for the year 2021 in appreciation for excellence in research presented by Manipal School of Life Sciences, MAHE, Manipal
  4. Certificate of appreciation for outstanding research publication for the year 2022 presented by Manipal School of Life Sciences, MAHE, Manipal
  5. “Certificate of Recognition” award presented by Stempeutics Research Pvt Ltd in March 2022 for outstanding contribution to the organization.
  6. “Employee of the Month” award  presented by Stempeutics Research Pvt Ltd in August 2018 for  excellence, dedication and outstanding performance
  7. Recipient of CSIR-SRF Fellowship
  8. “Young investigator award” at the 10th Asia Pacific Conference on Human Genetics held in Kuala Lumpur, Malaysia, December 5th-8th ,2012, for the paper entitled “Double C2 like domain beta (DOC2B) is down regulated through promoter hyper methylation and acts as a tumor suppressor in cervical carcinoma
  9. Best poster award” at Manipal University Scientific meet held on 12th January 2013
  10. Best poster award” at 10th Indo-Australian workshop on Epithelial Development, Function and Disease New Frontiers and Therapies held at Manipal University, Manipal from April 11th to13st 2014.
  11. Invention award, awarded by Intellectual Ventures India, Bangalore
  12. Travel Grant to attend 10th Asia Pacific Conference on Human Genetics held in Kuala Lumpur, Malaysia, December 5th-8th, 2012
  13. Serving as a member of Institutional Ethics Committee of Kasturba Medical College and Kasturba Hospital as an “Expert in stem cell research” from September 2024.
  14. Funding from ANRF, DBT and ICMR, Government of India for financial support for various research projects

Investigating the Role of miR-127/miR136 Cluster in Regulating Stemness Properties and its Contribution in the Pathogenesis of Cervical Cancer

Ms. Pratheeksha Hebbar

Elucidation of the Functional Role of miR-127/miR-136 Cluster-Kinesin Family Member 11 Axis in Modulating Stemness Properties in Cervical Cancer

Ms. Alfa Florence Rodrigues

Development of novel topical formulation containing bone marrow derived mesenchymal stromal cell conditioned medium for the treatment of diabetic foot ulcer

Mrs. Neema V Shetty

Development and Evaluation of a Novel, Mesenchymal Stromal Cell Secretome-Based Formulation for the Treatment of Melasma

Ms. Suchitra Prakash Talawar

Development of Human Mesenchymal Stromal Cell Derived Primed Conditioned Medium for Treating Inflammatory Diseases

Ms. Jahnavy Joshi

Development of Mesenchymal Stromal Cell Derived Extracellular Vesicles Nanocomposite Matrix

Ms. Shwetha Verma

Establishment of xeno-free conditions for ex vivo cultivation of human limbal epithelial and mesenchymal stem cells for therapeutic application in ocular surface pathologies

Ms. Sonali Mohapatra

Exploring the role of engineered bone marrow-derived mesenchymal stromal cells for the treatment of osteoarthritis

Mr. Anand